Concerta can cause fatigue

dosage

In the morning, regardless of meals.
Without pre-treatment with methylphenidate
Adult: initially 1 × daily 18 mg or 36 mg, possibly increase by (9–) 18 mg weekly up to a maximum of 1 × daily. 72 mg.
Youth: initially 1 × daily 18 mg, possibly weekly increase by (9–) 18 mg up to a maximum of 1 × daily. 72 mg.
Children> 6 years: initially 1 × daily 18 mg; possibly increase by (9–) 18 mg weekly up to a maximum of 1 × daily. 54 mg.
Switching from another methylphenidate preparation
Previously 3 × 5 mg: 1 × daily 18 mg.
Previously 3 × 10 mg: 1 × daily 36 mg.
Previously 3 × 15 mg: 1 × daily 54 mg.
Previously 3 × 20 mg: 1 × daily 72 mg.
Max. 1 × daily 72 mg (adults, youths) resp. 1 × daily 54 mg (children).

Contraindication

Pronounced states of anxiety, pronounced states of tension, pronounced agitation, severe depression, anorexia nervosa, psychotic symptoms, suicidal tendency, mania, schizophrenia, borderline personality disorder, alcohol abuse, drug abuse, Tourette's syndrome (including family history), hypertrophy, disease, BPH with residual urinary tract , cardiovascular diseases (including arrhythmias, severe hypertension, heart failure, angina pectoris, haemodynamically significant congenital heart defects, cardiomyopathy, myocardial infarction, canalopathies), arterial occlusive disease, cerebrovascular diseases, during and up to 14 days after MAO inhibitor therapy. Pregnancy «FI», lactation.